Associtate Professor, Medical Research Institute  Tel：86-27-68750121  Email：shuli@whu.edu.cn

Shu Li，PhD

Research Areas:

Mechanisms of innate antiviral immune responses

Selected Publications:

1. Luo WW, Li S, Li C, Lian H, Yang Q, Zhong B, Shu HB*(2016). iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING. Nat Immunol. 17(9):1057-66.

2. Luo WW, Lian H, Zhong B, Shu HB,Li S*(2016). Krüppel-like factor 4 negatively regulates cellular antiviral immune response.Cell Mol Immunol. 13(1):65-72.

3. An T, Li S, Pan W, Tien P, Zhong B, Shu HB, Wu S*(2015).DYRK2 Negatively Regulates Type I Interferon Induction by Promoting TBK1 Degradation via Ser527 Phosphorylation. PLoS Pathogens. 11(9):e1005179.

4. Zhang J, Hu MM, Shu HB, Li S*(2014). Death-associated protein kinase 1 is an IRF3/7-interacting protein that is involved in the cellular antiviral immune response. Cell Mol Immunol. 11: 245-252.

5. Mao AP, Li S, Zhong B, Li Y, Yan J, Li Q, Teng C, Shu HB*（2010）. Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of IFN-beta and cellular antiviral respose. J Biol Chem..285(13):9470-6.

6. Li S, Zheng H, Mao AP, Zhong B, Li Y, Liu Y, Gao Y, Ran Y, Tien P and Shu HB*.(2010).Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6. J Biol Chem. 285, 4291-4297.